Definition of 'to get one's knickers in a twist.' To get upset or angry, but its slang so not used outside of British conversation. For example: 'Don't get your knickers in a twist it was just a joke!'|@elliefoteinatou when somebody gets upset or annoyed over something that isn’t important. In Britain we would say it like “Don’t get your knickers in a twist!”|Stay calm. Getting upset isn't worth it.
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