MNK2 deficiency potentiates β-cell regeneration via translational regulation

In vivo chemical screen identifies stimulators of β-cell proliferation

eIF4E Antibody 9742S from Cell Signaling Technology

The UPR is necessary for HG-induced β-cell proliferation (related

Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing and alters beta cell identity in mice

R26-iCre efficiently labels most of cell lineages in pancreatic

In vivo screen identifies a SIK inhibitor that induces β cell proliferation through a transient UPR

Genetic modulation of Sik-family members regulates β cell

Restored UBE2C expression in islets promotes β-cell regeneration in mice by ubiquitinating PER1

Volume 18 Issue 9, September 2022

HG increases the proliferation of both mouse and human β-cells

MNK1 and MNK2 mediate adverse effects of high-fat feeding in distinct ways

MKNK2 - Wikipedia