Thursday Night Football: Niners WR Brandon Aiyuk (shoulder) out vs. Giants - Yahoo Sports

The Niners are a heavy favorite despite missing their top receiver.

Brandon Aiyuk

Niners WR Brandon Aiyuk (shoulder) inactive vs. Giants

49ers-Giants: Brandon Aiyuk missing first game since 2020

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Brandon Aiyuk and Ambry Thomas OUT vs. Giants; Inactives for #NYGvsSF

Javon Hargrave earns 49ers' highest PFF grade in Week 3 win vs. Giants – NBC Sports Bay Area & California

Javon Hargrave earns 49ers' highest PFF grade in Week 3 win vs. Giants – NBC Sports Bay Area & California

49ers-Giants: Brandon Aiyuk missing first game since 2020

49ers WR Brandon Aiyuk not expected to play vs. Giants, per report