PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends  Common to Rat and Human Hepatocytes/Microsomes and Implications for  Experimental Methodology

PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

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Multi-Well Array Culture of Primary Human Hepatocyte Spheroids for

Pharmaceutics, Free Full-Text

Incorporating Measures of Variability and Uncertainty into the Prediction of in Vivo Hepatic Clearance from in Vitro Data

Mechanistic Assessment of Extrahepatic Contributions to

In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance

Molecules, Free Full-Text

Prediction of hepatic clearance in human from in vitro data for

PDF) Clearance Prediction Methodology Needs Fundamental

Use of Segregated Hepatocyte Scaling Factors and Cross-Species

Incorporating Measures of Variability and Uncertainty into the Prediction of in Vivo Hepatic Clearance from in Vitro Data

Meeting the Challenge of Predicting Hepatic Clearance of Compounds

Mechanistic insights from comparing intrinsic clearance values

The Extended Clearance Concept Following Oral and Intravenous

PDF) Virtual experiments provide plausible explanations for IVIVE

Incorporating Measures of Variability and Uncertainty into the Prediction of in Vivo Hepatic Clearance from in Vitro Data